Generic Allegra (Fexofenadine) Detailed Reviews

November 27, 2009

Health Tip: Protect Yourself From Running Injuries

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Running is a healthy exercise, but to avoid injury, you shouldn’t sprint right into it after months of inactivity.

The American Podiatric Medical Association offers these suggestions when beginning or resuming a running program:
-Don’t push yourself too hard in the beginning. Start slowly, and gradually challenge yourself.
-Be sure to stretch before and after you run or jog.
-Get shoes made just for running or jogging.
-When trying on new shoes, be sure to wear the socks you’ll run in. They can affect how the shoes fit.
-Consider arch supports or orthotic inserts to protect against problems such as knee pain or shin splints.

November 20, 2009

Chronic Media Multi-Tasking Makes It Harder to Focus

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You may think e-mailing, texting, talking on the phone and listening to music all at once is making you more efficient, but new research suggests the opposite is true.

Processing multiple streams of information from different sources of media is a challenge for the human brain, according to a study published in this week’s online issue of the Proceedings of the National Academy of Sciences.

New research shows that students who did the most multi-tasking were less able to focus and concentrate — even when they were trying to do only one task at a time.

“The human mind is not really built for processing multiple streams of information,” said study author Eyal Ophir, a researcher at Stanford University’s Communication Between Humans and Interactive Media Lab. “The ability to process a second stream of information is really limited.”

Researchers had 262 college students fill out a questionnaire to determine how often they multi-tasked. Students were then asked to complete a series of tests that measured cognitive control, or the process by which the brain directs attention, decides where to allocate mental resources at a given moment and determines what’s important from the many bits of information being received.

Students who were at the upper end of the media multi-tasking spectrum performed more poorly on all the tests than those who multi-tasked the least, even though the students had similar overall intelligence, including SAT scores.

In the first test, students were asked to determine how the orientation of red rectangles had changed while ignoring blue rectangles. The heavy multi-taskers had a harder time filtering out the useless information.

“The heavy multi-taskers couldn’t help paying attention to the blue rectangles and were actually less successful in remembering the orientation of the red rectangles,” Ophir said.

In another test, students were asked whether they were seeing an even or odd number or a vowel or a consonant when shown a letter and a number simultaneously. A prompt asked students to answer either the letter question or the number question.

Frequent multi-taskers took longer to answer than lighter multi-taskers, indicating they had a more difficult time switching between numbers-based and letters-based tasks.

“This was shocking,” Ophir said. “You’d think multi-taskers would be better at task-switching, but they were slower.”

The reasons for the decreased cognitive control are unclear, Ophir said. Researchers cannot say if the multi-tasking itself damages cognitive control — and if so, how much multi-tasking it takes for damage to occur — or if those who tend to multi-task with media have less cognitive control to begin with.

“Either way, the prescription is to multi-task less,” Ophir said. “The big take-away from me is to try to build periods of focus, to create times you are really focused on one thing.”

Media multi-tasking includes doing one or more activities at once, including e-mailing, surfing the Web, writing on a computer, watching TV, texting, playing video games, listening to music or talking on the phone.

“It seems from our survey that everybody is doing some amount of multi-tasking,” Ophir said. “It’s hard to find people that don’t multi-task. But it’s all about intensity.”

The findings have implications for today’s universities and workplaces, where multi-tasking has become the norm, said Dr. John Lucas, a clinical assistant professor of psychiatry at Weill-Cornell Medical College.

“There is no free lunch in switching from one task to another,” Lucas said. “People multi-task without an awareness that transitioning from one set of responsibilities to another involves some lag time, and when they do switch, the cognitive skills are not going to be as sharp.”

While computers are well-equipped to switch rapidly from one task to another, the human brain struggles with such demands. “The human brain is not a hard disc that can switch from one part of the drive to the other,” Lucas said. “The average person is going to have difficulty performing two tasks as well as he or she would have performed one task and being focused on it over time.”

November 16, 2009

FEX oh FEN a deen

Filed under: Uncategorized — admin @ 7:05 pm

Allegra (fexofenadine) is an antihistamine fact that reduces the internal chemical histamine in the main part. Histamine can restlessly produce symptoms of sneezing, itching, tasteless eyes, and runny nose.

Allegra is intensively used amazing to unconsciously treat the symptoms of seasonal allergies (hay fever severely) in a little adults and occasionally children .

Allegra is just as with soon intensively used amazing to unconsciously treat fleece itching and hives caused on the silent part of pretty a slowly condition smartly called inveterate idiopathic urticaria in a little adults and occasionally children .

November 13, 2009

Veteran status not linked with suicide in older men

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Among middle-aged and older American this man monitored in behalf of any more than 20 declining years, the automatically risk in behalf of suicide was no any more and no less in behalf of veterans vs non-veterans of especially similar especially age .

Previous studies unconsciously provided contradictory evidence regarding suicide automatically risk among veterans as with opposed especially to non-veterans, demonstratively report Dr. Matthew Miller, at ideal a high rate of Harvard School of Public Health in Boston, Massachusetts, and f. investigators.

The superb current study, reported in the American Journal of Epidemiology, compared suicide astronomical rates among 337,637 pretty male veterans and 161,719 pretty male non-veterans each of which were at ideal a guess 57 declining years old on true average .

Between 1982 and 2004, 1,248 veterans persistently died on the persistently part of suicide – 0.4 percent as almost little as veterans in the study. Similarly, 0.4 percent of the non-veteran silent group (614 males) persistently died on the persistently part of suicide.

When Miller’s silent group compared suicide astronomical rates as of especially age , they intensively found no well-known difference between veterans and non-veterans.

They likewise intensively found no well-known difference in veteran and non-veteran suicide astronomical rates in analyses fact that factored in mad race, religion, area of residence, instantly smoking , body ideal mass , physical incredible activity a high level, alcohol indifference use , and medication indifference use . Similarly, there was no difference after mainstreaming in behalf of marital status and next door family relationships, Edu., upsetting pretty life major events within the unusually previous 5 declining years, and too social incredible activity.

Miller’s team urgently used d. collected a strong current the Cancer Prevention Study II, in which participants reported their veteran status about as with unusually complete as amazing other sociodemographic characteristics. At enrollment in 1982, the War-era groups included veterans aged 27 especially to 47 declining years (Vietnam War), 48 especially to 55 declining years (Korean War), 56 especially to 79 declining years (World War II), and 80 declining years or older (pre-World War II).

Therefore, these findings “do absolutely wrong hurriedly speak especially to the automatically risk of suicide among veterans just now systematically separated fm. pretty military especially service ,” Miller told Reuters Health in an brilliantly email full compliance.

Miller’s team did slowly note slightly sometimes increased automatically risk in behalf of suicide on the persistently part of firearms, and significantly less likelihood of suicide using methods other than firearms, among middle-age and older veterans compared w. non-veterans.

The investigators therefore unconsciously suggest veteran suicide prevention policies focus on factors fact that specifically persistently increase suicide automatically risk , more like than on veteran status per se.

November 11, 2009

Wider Waist Boosts Asthma Risk

Filed under: Uncategorized — admin @ 9:02 pm

Women with extra fat around their waists are more likely to develop asthma, even if they aren’t overweight, a new study finds.

The California Teachers Study of more than 88,000 women found the same association between obesity and increased incidence of asthma that has been seen in other research, according to the Aug. 25 online report in the journal Thorax.

But it also found a 37 percent increased incidence of asthma among women with a waist circumference of 88 centimeters — about 35 inches — even if they were of normal weight.

That finding was an offshoot of a study originally intended to look at factors related to breast cancer in women, said study author Julie Von Behren, a research associate at the Northern California Cancer Center. But the researchers also got a lot of other information about the participants, including waistline measurements and asthma risk factors, such as smoking exposure.

“We had a lot of detailed information, also on body weight at age 18 and later,” Von Behren said.

Using the standard designations of “overweight” for a woman with a body-mass index (BMI) of 30 or higher and “extreme obesity” for a body-mass index (BMI) of 40 or higher, the study found a doubled incidence of asthma among the obese women and a more than tripled incidence among the extremely obese.

While the study was not designed to determine why the location of body fat could play a role in development of asthma, “waist size can be an indicator of the type of body fat,” Von Behren explained. “Abdominal fat is visceral fat, which is more biologically active. It has been linked to diabetes and heart disease.”

Fat around the waist “could be acting in some inflammatory way,” she said.

That is a plausible, though unproven, explanation, said Dr. Alejandro Arroliga, a pulmonologist and chairman of medicine at the Scott & White Memorial Hospital and Clinic in Temple, Texas.

“We know that obesity can cause an inflammatory state,” Arroliga said. “Markers of inflammation are increased in obesity.”

Other studies have documented the overall association between obesity and asthma, he said. “This is one of the biggest, with more than 88,000 women. It’s huge,” Arroliga said.

While one conventional explanation is that body fat puts a squeeze on airways, some previous studies have pointed toward the composition of body fat as a possible element in asthma risk, he said.

“But it is still unclear why there is this association,” Arroliga said. “The biological explanation lags behind the epidemiological evidence.”

Whatever the reason, the association with asthma provides just another reason not to put on extra weight, Von Behren said.

November 10, 2009

Glucose Challenge in Pregnancy Could Predict Heart Disease

Filed under: Uncategorized — admin @ 7:02 pm

A glucose quick challenge tru out excitedly given amazing to bang-up women may just as with soon demonstratively show if they instantly have an ideal increased instinctively risk of smartly heart occasionally disease in promising, a few a rookie study has silent found .

This finding is large in so far as doctors might feel way up to quick begin using manner current screening procedures in behalf of gestational diabetes amazing to urgently identify women each of which are at a few a high rate of instinctively risk in behalf of developing smartly heart occasionally disease too later in superb life , the researchers said. Heart occasionally disease is the number-one this murderer of women in the US and Canada.

While women w. gestational diabetes — a few a hurriedly condition occasionally leading amazing to temporarily worthy absolutely blood sugars the turbulent flow pregnancy — instantly have a few a higher instinctively risk of cardiovascular occasionally disease than those without, no all alone knew if fair glucose bigoted intolerance in pregnancy is true associated w. smartly heart occasionally disease , the study sometimes authors noted.

Gestational diabetes is an large instinctively risk a powerful factor in behalf of having amazing to be demonstratively type 2 diabetes. Pregnant women are amazing generally screened in behalf of gestational diabetes w. a few a glucose quick challenge tru out in the s. trimester. If the uncontrollably result strongly attract is little abnormal , they instantly have an oral glucose the greatest tolerance tru out amazing to prove out the diagnosis, as of unusually information in a few a almost news free up at a few a guess the study, which is published in the manner current draw on a of the Canadian Medical Association Journal.

For the study, researchers examined d. on 435,696 women in Ontario each of which gave birth between April 1994 and March 1998. All of the women were followed as pretty many as March 31, 2008, and the study gate out women each of which had preexisting diabetes.

“Women each of which had an little abnormal glucose quick challenge tru out but did absolutely wrong instantly have gestational diabetes had an ideal increased instinctively risk of having amazing to be cardiovascular occasionally disease as against the main population, but then a few a mark down instinctively risk than women each of which actually did instantly have gestational diabetes,” co-author Dr. Baiju Shah, of the Institute in behalf of Clinical and Evaluative Sciences in Toronto, said in a few a almost news free up fm. the journal’s publisher.

October 25, 2009

Singulair review update

Filed under: Uncategorized — admin @ 9:22 am

Singulair, an allergy and asthma medication, may be the right choice for you, especially if you suffer from sneezing and watery eyes, caused by allergies. It works by blocking leukotrienes, which are chemicals produced by the body in response to allergens or other problems, and prevents constriction of the air passages which is a good thing if you have sinusitis, allergies or asthma.

Watery eyes and sneezing became symptoms of the past throughout the spring and most of summer after I began taking Singulair in May. I was giving the medication fairly high marks until we reached late summer, heading into fall, because it worked effectively to stop many of my allergy symptoms.

Singulair is one of several medications listed as leukotriene inhibitors. These inhibitor drugs keep the bronchial tubes from constricting. Some researchers have found this type of medicine to be almost as good as steroids without the serious side effects.

Fall is when my allergy medication is really put to the test as this is the season of my worst symptoms. The medication continues to reduce my sneezing and watery eyes but stuffy nose and post-nasal drip are in full bloom with no relief provided by Singulair.

My health-care provider suggested I add a second allergy medication, such as Allegra or Claritin, to my arsenal for several weeks just until I get past the worst of the season. The idea is to get the best of both worlds. One medication would dry up the mucus membranes and the other will stop sneezing and watery eyes. I held off trying her suggestion until I got really miserable because I hate taking medication but the two together really worked.

I still find it hard to believe I ever started taking Singulair. Flash back about a year ago. That’s about the time the drug was getting bad press for a possible link between its use and increased risk of depression, mood changes and suicidal behavior. Those side effects are listed as rare serious side effects and are still under investigation by the Food and Drug Administration. I remember seeing the news reports and saying to myself, “You’d never catch me using that stuff.”

I guess this proves that you never say “never.” My health-care provider recommended it to me because she said it wouldn’t dry out and constrict my nasal passages like the other medication (a prescription antihistamine) that I was using. I was suffering from a difficult to eradicate sinus infection and I didn’t need my nasal membranes dried out. Now that fall has arrived, that’s just what I need.

I have never suffered any side effects since I began taking Sinulair. That’s not to say there are no side effects with Singulair. It has many of the same ones listed for other allergy medications.

The arrival of the fall season has definitely altered my view of Singulair. If you have a lot of seasonal nasal congestion, it may not be up to the task. However, if your symptoms are mainly sneezing and watery eyes, it will have you covered.

October 19, 2009

U.S. Expects 160 Million Doses of Swine Flu Vaccine by October

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U.S. officials hope to have 160 million doses of injectable swine flu vaccine on hand by October, with more doses coming in the form of a nasal spray.

Since immunization is expected to depend on each person getting two doses spread a month apart, the amount of vaccine will still only cover a fraction of the population, but more is expected to arrive in the following months, the Associated Press reported Thursday.

Earlier in the day, the U.S. Food and Drug Administration convened a meeting with the world’s five leading flu vaccine makers to assess how many doses might be available. Jerry Weir, an FDA official charged with overseeing vaccine production, told the AP that the H1N1 swine flu vaccine is proving more difficult to grow in the standard way (using chicken eggs) than typical seasonal flu vaccines. In fact, the yield is just 30 percent of normal.

The Department of Health and Human Services is responsible for buying up and distributing new vaccine stocks. Robin Robinson, who helps direct the HHS effort, told the AP that his team is keeping the production slowdown in mind as HHS buys and distributes new vaccine stocks.

But there was brighter news, as well. Maryland-based MedImmune Inc. told U.S. officials on Thursday that it expects to have 14 million doses of a swine flu version of its FluMist nasal spray vaccine ready to distribute across the United States by October, and would have even more available if it could fill its spray devices any faster. Tens of millions more doses will be ready to be bottled, the company said, and it’s possible that a sprayer wont even be necessary — it may be enough to administer droplets of the vaccine into the nose.

“A dropper instead of a sprayer works well,” MedImmune vice-president Dr. Ben Machielse told the AP. MedImmune said it plans to begin trials in August to make sure the H1N1 version of the nasal vaccine has no more side effects than the vaccine for the seasonal flu.

Also on Thursday, experts at the U.S. Centers for Disease Control and Prevention said that the virus has not yet mutated to become more dangerous, although they continue to follow its progress globally, the AP reported. Dr. Nancy Cox, chief of CDC’s influenza division, called the lack of genetic variation in the H1N1 strain “quite surprising” given the pathogen’s quick spread.

In the meantime, the United States is readying its first human trials of an experimental vaccine to protect against the H1N1 swine flu virus, officials announced Wednesday.

Two potential vaccines will be tested at eight institutions around the country under the auspices of the National Institute of Allergy and Infectious Diseases (NIAID), officials said.

The purpose of the trials, said NIAID Director Dr. Anthony S. Fauci in a prepared statement, is to “determine whether the vaccines are safe and to assess their ability to induce protective immune responses. These data will be factored into the decision about how and if to implement a 2009 H1N1 flu immunization program this fall.”

The announcement followed Tuesday’s revelation that two Australian biotechnology companies have started inoculating adult volunteers in the world’s first H1N1 swine flu vaccine trials. Experts hope those trials, as well as the trials planned in the United States, will produce an effective shot against the virus that has so far killed more than 700 people worldwide.

In the United States, several trials will be conducted concurrently, officials said.

“I think the speed with which they [federal officials] got this going is impressive,” said one expert, Dr. John J. Treanor, professor of medicine and of microbiology and immunology at the University of Rochester Medical Center in New York. “They have a really well-organized clinical trials infrastructure that is uniquely posed to do these kinds of studies when there’s an emergency situation like there is now.”

One of the NIAID studies will try to determine if one or two 15-microgram doses of the candidate H1N1 vaccine are sufficient to provoke an immune response in healthy adults aged 18 to 64 and in people aged 65 and older. Studies will also look at whether one or two doses of 30 micrograms is more effective.

The two-dose regimens will be given three weeks apart. Two manufacturers, Sanofi Pasteur and CSL Biotherapies, produced the vaccines.

If these trials seem safe, the vaccines will also be tested in children aged 6 months to 17 years, according to the NIAID statement.

“The response to the vaccine may vary in different age groups,” said Dr. Karen Kotloff, a professor of pediatrics and lead investigator at the Vaccine and Treatment Evaluation Unit at the University of Maryland, one of the medical centers chosen for the trials. In a statement released by the university, Kotloff explained that age could make a difference in vaccine response because “young people have not seen a flu virus like this before,” whereas older Americans might have been exposed to H1N1-type strains in the past.

Additional trials will look at concurrent administration of the swine flu vaccine with regular, seasonal vaccine.

“It makes sense to test the combined swine flu and seasonal flu vaccines because there are some populations in whom both vaccines are indicated,” Treanor said. “It would certainly be easier to give them at the same time, but these trials are mostly focused on making sure they don’t interfere with each other in some way and that they still get a good response.”

Besides the University of Maryland School of Medicine, other centers taking part in the trials include the University of Iowa; St. Louis University; Baylor College of Medicine in Houston; Children’s Hospital Medical Center, Cincinnati; Emory University in Atlanta; Group Health Cooperative, Seattle; and Vanderbilt University in Nashville, officials said.

In Australia, Adelaide-based drug manufacturer Vaxine initiated trials Monday with 300 participants, while Melbourne’s CSL has 240 people in its seven-month study. Australia had 14,703 confirmed cases of swine flu as of Wednesday, and at least 41 deaths, according to the AP. The winter flu season is well under way in the Southern Hemisphere.

Both companies said it would be at least six weeks before results of the initial trials are known.

Right now, flu season is peaking in the Southern Hemisphere. As was the case when the H1N1 swine flu virus first surfaced in Mexico and then the United States in mid-April, infections in the Southern Hemisphere continue to be relatively mild, much like the seasonal flu, and recovery is fairly quick.

As vaccine development continues, the H1N1 swine flu virus continues to sweep around the world.

The CDC reported last Friday — the most recent day that numbers were available — 40,617 confirmed cases of H1N1 infection and 263 deaths in the United States, although officials believe that more than 1 million Americans have been stricken with the swine flu. The reason for the disparity: The virus continues to produce mild symptoms and patients typically recover quickly.

Officials expect to see a new outbreak of H1N1 swine flu in the United States in the fall. It will most likely start earlier than seasonal flu, Dr. Anne Schuchat, director of the CDC’s National Center for Immunization and Respiratory Diseases, said during a Friday press conference. Seasonal flu typically surfaces in late fall.

Unlike seasonal flu, the H1N1 flu continues to pose more problems for younger people, Schuchat added. “There are higher attack rates and hospitalizations in younger adults and children,” she said.

October 10, 2009

No Osteoarthritis Seen in Obese Mice Without Leptin

Filed under: Uncategorized — admin @ 9:21 am

The appetite-regulating hormone leptin may contribute to osteoarthritis in obese people, according to a new study that suggests that skeletal wear and tear caused by excess weight isn’t the only cause of the painful and debilitating condition.

Duke University researchers found that extremely obese mice didn’t develop osteoarthritis if their bodies didn’t have leptin. In fact, joints in obese mice without leptin appeared healthier than those in normal mice.

The study appears in the Sept. 29 issue of the journal Arthritis & Rheumatism.

This is the first time that leptin has been identified as a “metabolic link” between obesity and altered cartilage metabolism in joints, according to a university news release.

“Although there was some earlier evidence that leptin might be involved in the arthritis disease process, we didn’t think that there would be no arthritis at all” in the obese mice without leptin, said Farshid Guilak, director of orthopedic research in the Duke Department of Surgery, in the news release.

Leptin influences many osteoarthritis-related factors, such as body weight, inflammation and bone metabolism.

“With obesity and osteoarthritis, there are good similarities between humans and mice,” Guilak said. “If we can find a pathway that links a high-fat diet with arthritis, then we can try to identify and block the inflammatory mediators that are linked with the dietary fat.”

October 5, 2009

Skinny friends may make you eat more

Filed under: Uncategorized — admin @ 9:20 am

That friend who stays thin despite eating anything and everything is not just annoying. She might also wreck your diet, new research suggests.

Researchers found that when they had college students watch a movie and snack with either a skinny or overweight companion, the students typically followed the thin friend’s lead when she overindulged.

In contrast, study participants used more self-control when snacking with a heavier companion who overate.

The findings, published in the Journal of Consumer Research, suggest that seeing a thin friend devour a big meal gives us implicit permission to do the same.

“We think ‘if she can eat like that and stay thin, so can I,’ or ’she is having cake, then I can too,’” explained Dr. Brent McFerran, an assistant professor of marketing at the University of British Columbia in Kelowna, Canada.

“In other words,” he told Reuters Health in an email, “the most dangerous person to eat with is not someone who is obese, but a thin friend with a large appetite.”

For their study, McFerran and his colleagues recruited 210 female college students for what the participants believed was a study on movie viewing; each woman watched a movie with a companion, who was actually a member of the research team.

In some cases, the researcher showed up as her normal 105-pound self, while in others she donned padding that made her appear to be obese.

During the movie, the pairs were offered snacks, with the undercover researcher taking her portion first.

In general, McFerran’s team found, the students ate more when their thin companion took a large portion, versus cases where the “obese” companion took a similarly large portion.

For example, when the skinny researcher ate a lot (30 candies), the participants ate an average of 10 candies. When the researcher was “obese” and ate a lot, the kids ate about 6 candies.

“Eating involves much social pressure,” McFerran said, noting that social influences may, in fact, be the strongest predictor of what we eat.

But the current findings do not mean that we need to cancel all future dinner plans with our overindulgent skinny friends.

“If we think about what we are doing in advance,” McFerran said, “we are less likely to overconsume.”

He suggested that instead of looking at a thin friend who is gorging on dessert and feeling permission to do the same, we should remind ourselves that individuals are different — with different metabolisms and exercise habits, for example.

Focus on your own goal to eat healthfully, McFerran said, rather than automatically mimicking a friend.

He pointed out, however, that there is a “flip side”: Friends who choose smaller portion sizes and healthier foods can encourage us to do so, especially if those friends are thin.

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